Fig. 5

Association between gut microbiota and inflammatory markers in BD patients. (i) Serum levels of IL-6 were positively correlated with Enterobacter, Pseudomonas and Leuconostoc abundance, but negatively associated with Cloacibacillus abundance (P < 0.05). (ii) Serum CRP levels were positively correlated with Prevotella abundance, but negatively associated with Butyricicoccus, Lachnospiraceae incertae sedis and Dorea abundance (P < 0.05). (iii) TNF-α levels correlated positively with Parabacteroides, Clostridium IV and Bilophila abundance but negatively with Prevotella abundance (P < 0.05)