Fig. 1
From: Role of trazodone in treatment of major depressive disorder: an update
Pharmacokinetic properties of trazodone IR (immediate-release formulation, purple) dosed at 100 mg three times per day, and trazodone XR (extended-release, red) dosed at 300 mg once daily at night, showing plasma drug levels with respect to the minimum antidepressant concentration of 0.65 Mg/L over a 24 h period. (From Stahl [22])