Table 1 Demographic characteristics and incidence of major mental disorders between the offspring of parents with or without migraine
From: Risk of major mental disorders in the offspring of parents with migraine
|  | Offspring of parents with migraine (n = 22,747) | Offspring of parents without migraine (n = 227,470) | p-value |
|---|---|---|---|
Age (years, SD) | 8.88 (6.97) | 8.89 (6.98) | 0.851 |
Birth-year (n, %) | Â | Â | 0.998 |
 1980–1984 | 5041 (22.2) | 50,415 (22.2) |  |
 1985–1989 | 41.61 (18.2) | 41,758 (18.4) |  |
 1990–1994 | 4358 (19.2) | 43,506 (19.1) |  |
 1995–1999 | 4138 (18.2) | 41,174 (18.1) |  |
 ≥ 2000 | 5053 (22.2) | 50,617 (22.2) |  |
Sex (n, %) | Â | Â | 1.000 |
 Male | 11,867 (52.2) | 118,670 (52.2) |  |
 Female | 10,880 (47.8) | 108,800 (47.8) |  |
Parents with migraine (n, %) | Â | Â | Â |
 Fathers | 6379 (28.0) |  |  |
 Mothers | 16,387 (72.0) |  |  |
Parental mental comorbidities (n, %) | Â | Â | Â |
 Schizophrenia | 247 (1.1) | 1564 (0.7) | < 0.001 |
 Bipolar disorder | 415 (1.8) | 1611 (0.7) | < 0.001 |
 Depressive disorder | 1605 (7.1) | 5868 (2.6) | < 0.001 |
Incidence of major mental disorder (n, %) | Â | Â | Â |
 ASD | 71 (0.3) | 651 (0.3) | 0.479 |
  Age at diagnosis (years, SD) | 9.51 (5.78) | 8.40 (5.56) | 0.113 |
 ADHD | 541 (2.4) | 3798 (1.7) | < 0.001 |
  Age at diagnosis (years, SD) | 9.09 (3.63) | 8.92 (3.76) | 0.339 |
 Schizophrenia | 71 (0.3) | 653 (0.3) | 0.481 |
  Age at diagnosis (years, SD) | 19.86 (3.58) | 20.40 (4.11) | 0.288 |
 Bipolar disorder | 81 (0.4) | 531 (0.2) | < 0.001 |
  Age at diagnosis (years, SD) | 22.09 (5.22) | 21.32 (4.23) | 0.158 |
 Depressive disorder | 456 (2.0) | 3189 (1.4) | < 0.001 |
  Age at diagnosis (years, SD) | 20.81 (4.66) | 21.16 (4.33) | 0.108 |
Level of urbanization (n, %) | Â | Â | 1.000 |
 1 (most urbanized) | 4722 (20.8) | 47,220 (20.8) |  |
 2 | 7116 (31.3) | 71,160 (31.3) |  |
 3 | 2842 (12.5) | 28,420 (12.5) |  |
 4 | 2350 (10.3) | 23,500 (10.3) |  |
 5 (most rural) | 5717 (25.1) | 57,170 (25.1) |  |
Income-related insured amount (n, %) | Â | Â | 1.000 |
 ≤ 19,100 NTD/month | 2950 (13.0) | 29,500 (13.0) |  |
 19,001 ~ 42,000 NTD/month | 7635 (33.6) | 76,350 (33.6) |  |
 > 42,000 NTD/month | 12,162 (53.4) | 121,620 (53.4) |  |