Table 2 Demographic characteristics, all randomized patients/safety population
From: A pooled analysis of the efficacy of sertraline in women, with a focus on those of childbearing age
Characteristics | Total cohort |  | All Females |  | Females in reproductive age group (18–44 years) | |||
|---|---|---|---|---|---|---|---|---|
| Â | Placebo | Sertraline | Â | Placebo | Sertraline | Â | Placebo | Sertraline |
|  | n = 670 | n = 1162 |  | n = 404 | n = 693 |  | n = 248 | n = 403 |
Age, years | ||||||||
Mean (SD) | 41.2 (12.50) | 45.4 (15.98 | Â | 41.3 (12.71) | 44.7 (15.89) | Â | 32.9 (6.73) | 33.2 (6.61) |
Range | 18–85 | 19–91 |  | 18–85 | 19–89 |  | 18–45 | 19–44 |
Sex, n (%) | ||||||||
Female | 404 (60.3) | 693 (59.6) | Â | 404 (100) | 693 (100) | Â | 248 (100) | 403 (100) |
Male | 266 (39.7) | 469 (40.4) | Â | - | - | Â | - | - |
Ethnicity, n (%) | ||||||||
White | 540 (91.5) | 865 (92.5) | Â | 317 (92.7) | 513 (92.4) | Â | 199 (91.7) | 303 (90.7) |
Non-white | 50 (8.5) | 70 (7.5) | Â | 25 (7.3) | 42 (7.6) | Â | 18 (8.3) | 31 (9.3) |
BMI, kg/m2 | ||||||||
Mean (SD) | 25.7 (5.55) | 25.0 (5.11) | Â | 25.4 (5.84) | 24.8 (5.62) | Â | 25.3 (6.26) | 24.4 (6.01) |
Baseline HAM-D17 score | ||||||||
Mean (SD) | 23.4 (3.47) | 23.7 (3.58) | Â | 23.3 (3.42) | 24.0 (3.51) | Â | 23.2 (3.21) | 23.8 (3.32) |
Baseline HAM-D17 severity, n (%) | ||||||||
<= 21 | 154 (27.5) | 276 (26.5) | Â | 93 (27.8) | 144 (23.5) | Â | 60 (28.2) | 83 (23.1) |
22–23 | 154 (27.5) | 247 (23.8) |  | 92 (27.5) | 142 (23.2) |  | 61 (28.6) | 91 (25.3) |
24–25 | 116 (20.7) | 230 (22.1) |  | 71 (21.2) | 147 (24.0) |  | 45 (21.1) | 91 (25.3) |
>= 26 | 136 (24.3) | 287 (27.6) | Â | 79(23.6) | 179 (29.2) | Â | 47 (22.1) | 94 (26.2) |
Baseline CGI score | ||||||||
Mean (SD) | 4.3 (0.60) | 4.3 (0.60) | Â | 4.2 (0.58) | 4.3 (0.59) | Â | 4.2 (0.56) | 4.3 (0.60) |
=Baseline CGI severity, n (%) | ||||||||
< 4 | 34 (5.3) | 46 (4.7) |  | 20 (5.1) | 23 (3.9) |  | 12 (5.1) | 14 (3.9) |
4 | 419 (65.4) | 643 (65.7) | Â | 265 (67.9) | 387 (65.4) | Â | 162 (68.4) | 232 (65.0) |
5 | 174 (27.1) | 268 (27.4) | Â | 96 (24.6) | 169 (28.5) | Â | 59 (24.9) | 102 (28.6) |
>=6 | 14 (2.2) | 22 (2.2) | Â | 9 (2.3) | 13 (2.2) | Â | 4 (1.7) | 9 (2.5) |