Fig. 2

Relative risk (RR) incl. 95% confidence interval of single vs. multiple imputation adverse drug reactions (ADRs) (A) according to the affected organ system and (B) in a selection* of individual ADRs in older vs. younger patients. RR > 1 implies a higher ADR-risk for older patients compared to younger patients; RR < 1 implies a lower ADR-risk for older patients compared to younger patients. *selection is based on ADRs for which we detected significant differences between the two age groups. (s) single imputation ADR; (m) multiple imputation ADR; w/ with; w/o without; EPS extrapyramidal symptoms; UL upper limit