Skip to main content

Table 2 Relative risk for adverse drug reactions of patients according to sex and diagnosis in patients ≥ 65 vs. < 65 years

From: Psychotropic drug-induced adverse drug reactions in 462,661 psychiatric inpatients in relation to age: results from a German drug surveillance program from 1993–2016

 

Patients ≥ 65 years of age

Patients < 65 years of age

 ≥ 65 vs. < 65

N patients with ADR

N patients (all)

% of patients with ADR

N patients with ADR

N patients (all)

% of patients with ADR

RR (95% CI)

Total

1212

99,099

1.22%

4517

363,562

1.24%

0.98 (0.95–1.02)

Sex

 Females

863

67,655

1.28%

2020

290,935

0.69%

1.84 (1.76–1.92)

 Males

349

31,444

1.11%

2949

172,627

1.71%

0.65 (0.62–0.68)

Diagnosis (ICD-10)

 Organic disorders (F0)

337

32,677

1.03%

242

23,732

1.02%

1.01 (0.89–1.15)

 Substance-related disorders (F1)

14

2217

0.63%

136

18,420

0.74%

0.86 (0.72–1.02)

 Schizophrenia (F2)*

170

15,940

1.07%

2078

142,097

1.46%

0.73 (0.69–0.77)

 Depressive disorders (F3 without F30, F31.0–F31.2)*

626

40,685

1.54%

1402

117,313

1.20%

1.29 (1.22–1.36)

 Acute mania (F30, F31.0–F31.2)*

36

2344

1.54%

241

10,823

2.23%

0.69 (0.60–0.79)

 Others (F4–F9)*

29

5236

0.55%

385

51,167

0.75%

0.74 (0.66–0.82)

  1. ADR adverse drug reaction; N number (of); RR relative risk; CI confidence interval; ICD-10 International Classification of Disease, 10th Version
  2. *Indicates a significant finding
Back to article page

Annals of General Psychiatry

ISSN: 1744-859X