Fig. 2

Summary of the participant flow in the EDIT-B study. (1) The clinician includes the participant in EDIT-B study and evaluate the diagnosis; (2) After inclusion, a blood sample is taken from the participant at the respective centre; (3) Blood sample is sent to the central laboratory that performs the biological analysis; (4) Data analysis is done using EDIT-B signature before clinical and EDIT-B results are compared for final analysis