Table 3 Multivariate associations of PM2.5, APOE genotype and MMSE score
From: The independent role of fine particulate matter and genetic liability on cognition in older adults
Adjusted Beta (95% CI) a | p-value | |
|---|---|---|
PM2.5 | -0.0235 (-0.0345, -0.0124) | < 0.0001 |
APOEgenotype | ||
E3/E3 | Ref. | |
E3/E4 | -0.0174 (-0.0906, 0.0558) | 0.6421 |
E4/E4 | -0.2827 (-0.6004, 0.0350) | 0.0811 |
Age | -0.0453 (-0.0537, -0.0370) | < 0.0001 |
Sex | ||
Male | Ref. | |
Female | 0.1275 (0.0674, 0.1877) | < 0.0001 |
Education | ||
Illiteracy, self-study, or elementary school | Ref. | |
Junior high school | 1.4761 (1.3633, 1.5889) | < 0.0001 |
Senior (Vocational) high school | 2.3851 (2.291 L, 2.4790) | < 0.0001 |
University (College) | 2.9575 (2.8622, 3.0528) | < 0.0001 |
Master and above | 3.2197 (3.0793, 3.3600) | < 0.0001 |
Median household income | 0.0014 (0.0003, 0.0025) | 0.0098 |
CV household income | 0.0002 (-0.0001, 0.0004) | 0.2369 |
Urbanization | ||
1 (Urban) | Ref. | |
2 (Sub-urban) | -0.1803 (-0.3489, -0.0117) | 0.0361 |
3 (Rural) | -0.2138 (-0.5268, 0.0992) | 0.1806 |